Models of dopaminergic modulation
نویسندگان
چکیده
منابع مشابه
Computation with Dopaminergic Modulation
Definition Dopamine (DA) is a neuromodulator released by midbrain neurons with widespread projections throughout the brain. Dopaminergic modulation has diverse effects on cellular, motor and cognitive functions, including reinforcement learning, working memory and attention. Dysregulation of dopamine also plays a central role in the breakdown of these functions in disorders such as Parkinson's ...
متن کاملDopaminergic Modulation of Risk-based
Psychopharmacological studies have implicated the mesolimbic dopamine (DA) system in the mediation of cost/benefit evaluations about effort-related costs associated with larger rewards. However, the role of DA in risk-based decision making remains relatively unexplored. The present study investigated how systemic manipulations of DA transmission affect risky choice assessed with a probabilistic...
متن کاملDopaminergic Modulation of Arousal in Drosophila
BACKGROUND Arousal levels in the brain set thresholds for behavior, from simple to complex. The mechanistic underpinnings of the various phenomena comprising arousal, however, are still poorly understood. Drosophila behaviors have been studied that span different levels of arousal, from sleep to visual perception to psychostimulant responses. RESULTS We have investigated neurobiological mecha...
متن کاملDopaminergic modulation of human bronchial tone.
BACKGROUND Dopamine exerts inhibitory and excitatory effects on different systems. Its effect on human bronchial tone is controversial. It has been reported that dopamine has no acute effect on human airways from normal subjects or those with asthma background. However, inhaled or infused dopamine decreased histamine-induced bronchoconstriction in both normal and asthmatic subjects. METHODS W...
متن کاملHypothalamic modulation of the midbrain dopaminergic system
Ventral tegmental area (VTA) dopaminergic (DAergic) and GABAergic neurons are critically involved in mechanisms of reward, reinforcement and emotional arousal. The hypothalamus regulates the homeostatic drive to eat and sends a massive output to the VTA, including projections from neurons containing orexins, the novel neuropeptides, which potently modulate arousal and feeding. Single-unit extra...
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ژورنال
عنوان ژورنال: Scholarpedia
سال: 2011
ISSN: 1941-6016
DOI: 10.4249/scholarpedia.4215